Some authors reported reduced clonogenic potential of HPCs from WASKO mice and WAS patients33 while others found normal CFU formation capabilities and maintenance of WAS HPCs.34,42 We found a slight, although not significant, reduction in the clonogenic potential of WASKO-HPCs compared to WT-HPCs, indicating that the absence of WASp does not play a relevant role in this property of HPCs, at least under this experimental conditions. Here, WAS is linked to Wiskott-Aldrich syndrome.