The aim of this study was therefore to investigate LOX protein expression in prostate tumor epithelial cells, tumor stroma, tumor-adjacent non-malignant prostate epithelium (TINT epithelium) and in tumor-adjacent non-malignant tumor stroma (TINT stroma) and relate LOX expression in the different compartments to histopathological and clinical parameters as well as to outcome in a historical cohort of prostate cancer managed by watchful waiting (see [12] for details). This evidence concerns the gene LOX and neoplasm.