In a recent study conducted by Chik et al., overexpression of sialyl Tn antigens was correlated with upregulation of alpha 2,6 sialyltransferase gene (ST6GALNAC1) and a decrease in core 1 synthase gene (C1GALT1) in the mucinous colorectal cancer cell line LS174T (44). The gene discussed is C1GALT1; the disease is colorectal cancer.