The AG and AG + GG variants of JAZF1 (rs864745) were consistently associated with increased T2DM risk in both female [AG: OR 2.0 (95 % CI 1.2–3.9), p = 0.02); AG + GG: OR 1.9 (95 % CI 1.1–3.6), p = 0.03] and male subjects (AG: OR 1.8 (95 % CI 1.0–3.1), p = 0.04; AG + GG: OR 1.7 (95 % CI 1.0–2.9), p = 0.03). The gene discussed is JAZF1; the disease is type 2 diabetes mellitus.