Raymond et al. (2009) have shown that epithelial cells, from either a murine or human source, when stimulated by B. anthracis, secrete CXCL-8/KC, IL-6, and CXCL-2. In an attempt to gain access to the potential interactions that could exist between lung cells, Chakrabarty et al. (2007) used a lung slice model of in vitro infection, thus retaining the complex architecture of the lung tissue. Through immunohistochemistry, they showed that exposure to B. anthracis spores induced production of IL-6 and CXCL-8 by alveolar epithelial cells and macrophages. The gene discussed is CXCL8; the disease is infection.