These data are also similar to a positive correlation reported between PDGF-CC levels in plasma and worse outcomes in ischemic stroke patients (Rodríguez-González et al., 2013), and with our previous study showing elevated tPA-inhibitor complexes in the CSF of the most severe TBI patients (Sashindranath et al., 2012). The gene discussed is CXCR1; the disease is ischemic stroke.