None of the MHC II genes or the known direct FOXP1 target HIP1R were significantly upregulated in both GCB-DLBCL lines (Figure 3b), whereas HIP1R and five CIITA-regulated genes (CD74, HLA-DQB1, HLA-DQB2, HLA-DOA, HLA-DMA) were significantly upregulated in both FOXP1-depleted OCI-Ly3 and HBL-1 lines. The gene discussed is CD74; the disease is diffuse large B-cell lymphoma.