Previously reported 2-month TB treatment biomarkers, such as coagulation factor V, thrombospondin-4, and alpha-1-antitrypsin10, 13, and previously reported diagnostic biomarkers, such as apolipoprotein A-II14 and fibrinogen beta chain15, were also identified by iTRAQ-2DLC-MS/MS analysis in cured and untreated TB patients in our study. The gene discussed is THBS4; the disease is tuberculosis.