The following microRNAs were selected: miR-21, which promotes cell proliferation and may accelerate tumorigenesis [8, 9, 20]; miR-155, which interacts with TP53 INP1 and transforming growth factor β (TGF-β) [11, 21, 22]; miR-96 and miR-217, which may act as a tumor suppressors, inhibiting the KRAS-signaling pathway [13, 14] also miR-148a and miR-196a, which are frequently included in experimental panels for pancreatic carcinoma diagnosis [23–29]. This evidence concerns the gene TP53 and exocrine pancreatic carcinoma.