It was recently reported to predict the outcomes in patients with HCC, nonalcoholic fatty liver disease, and liver transplantation [12, 17, 18], Although clinical risk factors of bacterial infection, such as advanced liver diseases or gastrointestinal bleeding, are well characterized [6, 8, 19–21], data on both CRP and NLR as serologic markers are scarce in such patients with advanced diseases. This evidence concerns the gene CRP and bacterial infectious disease.