Some of the genes bearing mutations in the SMZL cases investigated here, including PRSS1 [40], PCLO [41, 42], CSMD1 [26, 43], HERC2 [44], and MUC12 [45] have been previously described to be mutated in other tumor entities, but not in SMZL. The gene discussed is CSMD1; the disease is neoplasm.