CDK6 and hepatocellular carcinoma: Furthermore, we found that miR-214 mimicking oligonucleotides dose-dependently abrogated the expression of luciferase activity of pGL3-E2F2, CDK3, CDK6-3′-UTR in HCC cells, and such suppressive effects could be reversed by anti-miR-214 oligonucleotides (Figure 4C–4E).