By specifically looking for RNAs that are bound to SUZ12, a component of the polycomb repressive complex 2 (PRC2), in chemically cross-linked samples of human prostate cancer cell lines, Coolen and colleagues identified a number of protein coding RNAs that bind to SUZ12 with affinities comparable to that of lncRNAs [94]. This evidence concerns the gene SUZ12 and prostate cancer.