To determine whether NIAM protein expression in primary B-cell lymphoma is inversely associated with the miR-155 expression level we analyzed primary cases of CLL (high miR-155), DLBCL (variable miR-155) and BL (low miR-155) by immunohistochemistry for NIAM and qRT-PCR for miR-155. This evidence concerns the gene TBRG1 and B-cell chronic lymphocytic leukemia.