AKT1 and neoplasm: A proteomic signature of AKT pathway inhibition by GSK2141795 was identified through RPPA analysis of SKOV3 tumours grown in vivo, SKOV3 monolayers in vitro and PEO4 monolayers in vitro. Consistent effects of treatment with GSK2141795 across the range of environments studied (each compared to a DMSO control) were identified using a Rank Product meta-analysis.