Koch et al. made a similar observation, concluding that some APOE polymorphisms, i.e., APOE –219G>T, 113G>C, 334T>C (APOE*4), and 472C>T (APOE*2) either alone or in combination do not represent genetic markers of the risk of ISR or stent thrombosis in German patients with coronary artery disease [21]. This evidence concerns the gene APOE and coronary artery disorder.