miR-143 was dramatically upregulated in HBV-related HCC and promoted cancer cell invasion, migration and tumor metastasis by repression of FNDC3B expression [26], but miR-143 also repressed glioma cell migration, invasion, tube formation and slowed tumor growth and angiogenesis in a manner associated with N-RAS downregulation [32]. The gene discussed is NRAS; the disease is neoplasm.