A wide variety of genetic risk factors likely involved in susceptibility to develop IPF have been described including common variants in MUC5B [2], TERT, a component of telomerase [2, 3], Toll-interacting protein (TOLLIP) [4], surfactant protein A and B [5] and polymorphisms within the major histocompatibility complex (MHC) [6]. This evidence concerns the gene HLA-C and idiopathic pulmonary fibrosis.