ATG5 and neoplasm: Although the number of colon tumors was not significantly different between Ctr and Atg5-deficient mice, the tumor maximum (4.5 mm in Ctr and 3.5 mm in Atg5-deficient mice, p = 0.030) and total sizes (28.1 mm in Ctr and 20.7 mm in Atg5-deficient mice, p = 0.036) were significantly smaller in Atg5-deficient mice than in Ctr mice.