Similarly, we observed that in subjects developing persistent arthralgia, the levels of IL-7 and VEGF were significantly elevated at most or all of the time points examined when compared to healthy donors whereas in subjects that fully recovered from MAYV infection, they were only significantly induced during the convalescent phase (IL-7) or 3 and 6 months post-infection (VEGF)(Fig 4). The gene discussed is VEGFA; the disease is infection.