In the overall analysis, we found a significant strong association between BRCA2 N372H polymorphism and increased risk of ovarian cancer in the homozygote model (HH versus NN) with OR 1.22 (95% CI, 1.01–1.48, P = 0.037) (Table 2, Fig. 2C). The gene discussed is BRCA2; the disease is ovarian carcinoma.