ERBB2 and neoplasm: The transcriptional network recognized a putative functional association interposing miR-125a between ERBB2/ERBB3, TP53 and CDKN1A. The relationship between miR-125a and ERBB genes family has indeed been demonstrated in several tumors [29], whereas the induction of a p53-dependent tumor suppression specifically induced by miR-125a inhibition has been recently described by us in MM [30].