IL10 and infection: Interestingly, although the results indicate their ability to induce protective immunity against M. tuberculosis by enhancing effector populations of CD4 and CD8+ T cells and increasing IFN-γ [170–175], they also induce regulatory T cells and IL-10 for potential inhibition of autoimmune manifestations [147–149, 176–178], demonstrating a practical situation of success in controlling infection with M. tuberculosis with effector/regulator concurrent mechanisms.