MC4R and obesity due to melanocortin 4 receptor deficiency: These single nucleotide polymorphisms (SNPs) were fat mass and obesity-associated (FTO) (rs9939609) T>A, glucosamine-6 phosphate deaminase 2 (GNPDA) (rs10938397) A>G, potassium channel tetramerization domain containing (KCTD15) (rs11084753) G>A, melanocortin receptor 4 (MC4R) (rs17782313) T>C, mitochondrial carrier homolog 2 (MTCH2) (rs10838738) A>G, neuronal growth regulator 1 (NEGR1) (rs2815752) A>G, SH2B adapter protein 1 (SH2B1) (rs7498665) A>G, and transmembrane protein 18 (TMEM18) (rs6548238) C>T.