Although plasma BST2 levels did not significantly differ in CRC patients at different stages (Supplemental Figure 1), higher plasma BST2 levels were observed in older patients (2.61 ± 1.34 versus 2.03 ± 1.63; p = 0.03), mucinous carcinoma (4.63 ± 0.45 versus 2.28 ± 1.48; p = 0.05), and CRC patients with hypoalbuminemia (4.14 ± 2.46 versus 2.12 ± 1.14; p < 0.01) (Supplemental Table 3). Here, BST2 is linked to Hypoalbuminemia.