SELPLG and hydrops fetalis: 2014; le Roux et al. 2007; Sodowski et al. 2011). In the current study, there is a significant decrease in PYY gene expression in female but not male offspring of HF-fed mothers, which may in part contribute to the observed obese phenotype at weaning. Consistent with evidence that CLA stimulates PYY secretion in a murine cell line (STC-1) (Hand et al. 2012), CLA promotes increased PYY gene expression in both male and female offspring from CLA supplemented mothers.