CD4 and tuberculosis: Indeed, antigen-specific CD4+ T-cell and antibody responses were elicited by AS02-adjuvanted Mtb72F vaccines in various adult populations [15, 19–21], and by AS01-adjuvanted M72 vaccines in populations of healthy adults in TB-endemic and non-endemic regions [19, 22, 23], HIV-1-infected adults in Switzerland [24], and healthy infants in The Gambia [25].