We [66] and others [67] have previously shown that the expression of above median levels of LAAs, such as SSX2IP alone, or in combination with SURVIVIN and receptor for hyaluronan-mediated motility (RHAMM), in presentation AML patients who lack cytogenetic rearrangements, can predict survival following conventional treatment (chemotherapy). The gene discussed is SSX2IP; the disease is acute myeloid leukemia.