Mutations in the putative TRM7 homolog FTSJ1, have been strongly associated with non-syndromic X-linked mental retardation in multiple studies [14], and tRNAPhe from neuroblastoma cells and Ehrlich ascites tumors has a substantial portion of its tRNAPhe lacking Cm32 and Gm34 [15]. Here, FTSJ1 is linked to neuroblastoma.