Ten cancer-related pathways including pathways in cancer, pancreatic cancer, melanoma, prostate cancer, chronic myeloid leukemia, colorectal cancer, glioma, small cell lung cancer, bladder cancer, and non-small cell lung cancer, were enriched with the mRNAs, another 5 non-cancer related pathways such as MAPK signaling pathway, focal adhesion, cell cycle, neurotrophin signaling pathway, T cell receptor signaling pathway were also enriched. This evidence concerns the gene BDNF and melanoma.