To further confirm whether the cell growth and growth was induced through apoptosis induction, cell cycle and apoptosis analyses were performed using PI staining and annexin v assays demonstrated that targeting NRIP1 in breast cancer cells significantly induced apoptosis irrespective of breast cancer subtypes, suggesting that the suppression of cell growth and growth is due to the induction of apoptotic cell death. Here, NRIP1 is linked to breast carcinoma.