Antiatherogenic phenotypes include (a) M2 and (b) M4, which are CXCL4-induced and express low CD163 levels [216], (c) M(Hb), which are activated by hemoglobin-haptoglobin complexes [217], and (d) Mhem, heme-inducible macrophages, which are characteristically located in intraplaque hemorrhage sites, with high heme oxidase levels induced by Activating Transcription Factor-1 (ATF-1) [23, 24, 213]. Here, ATF1 is linked to hemorrhage.