On March 2008, the patient presented a complex clinical picture including an interstitial pneumonitis by Mycoplasma pneumoniae and Chlamydia pneumoniae, Epstein Barr and cytomegalovirus infections, tubulointerstitial nephritis, severe lymphopenia, and marked reduction of CD4 (214 cells/μL, Tables 1 and 2). This evidence concerns the gene CD4 and lymphopenia.