SOD1 and amyotrophic lateral sclerosis: These results suggest that muscle expression of SOD1G93A impinges muscle differentiation and might alter the identity of muscle cells in line with previous studies that demonstrate the impairment of myofiber-associated skeletal muscle satellite cells function in SOD1-G93A mice [39] and the altered expression of myogenic regulatory factors in the mouse model of amyotrophic lateral sclerosis [40].