SIRT1 and myocardial infarction: Compared with Ad-GFP-treated diabetic MI/R rats (DIR), up-regulation of SIRT1 (Ad-SIRT1) significantly elicited a significant recovery in LVDP and ±LV dP/dtmax in diabetic MI/R rats (n = 8, P < 0.05 or P < 0.01, Fig. 2c–e).