CD8A and Increased total eosinophil count: Wells et al. reported that the transfer of CD8+ T cells from OT-I transgenic mice resulted in a marked suppression of airway eosinophilia and Th2 lung cytokine responses at least partly through the stimulation of IL-12 in the lung, reflecting their bias toward the cytotoxic type 1 (Tc1) phenotype [33].