MEF2C and acute myeloid leukemia: Specifically, patients with high MEF2C expression less likely had CBF translocations (inv(16): P = 0.007 and t(8;21): P < 0.001) or normal karyotype AML (P < 0.001); conversely, they were more likely to have leukemias with monosomy 7 (P < 0.001) and abnormalities involving 11q23 (P < 0.001).