TRAF3IP1 encodes the IFT-B subunit, IFT54, and its inactivation is embryonic lethal and causes characteristic ciliopathy phenotypes, including neural developmental defects, polydactyly and microphthalmia in mice11, and curved body axis, pronephric cysts and retinal degeneration in the elipsa zebrafish mutant12, 13. The gene discussed is IFT54; the disease is microphthalmia.