TRAF3IP1 encodes the IFT-B subunit, IFT54, and its inactivation is embryonic lethal and causes characteristic ciliopathy phenotypes, including neural developmental defects, polydactyly and microphthalmia in mice11, and curved body axis, pronephric cysts and retinal degeneration in the elipsa zebrafish mutant12, 13. This evidence concerns the gene IFT54 and ciliopathy.