In our current work, however, we did not find high levels of IL-2 or TNF-α in those patients (or controls) with expanded CD4+NKG2D+ T cells; on the contrary, significant and negative correlations between the numbers of CD4+NKG2D+ T cells and levels of these pro-inflammatory cytokines were found in cervical cancer samples. This evidence concerns the gene CD4 and cervical carcinoma.