There was no association between clinico-demographic parameters, endoscopic parameters, or AMACR or cyclin D1 expression levels and the presence of prevalent neoplasia or advanced prevalent neoplasia (Tables 1 and 2 and data not shown); high p53 expression (>5%), however, was associated with the presence of advanced prevalent neoplasia (Table 2). The gene discussed is TP53; the disease is neoplasm.