CXCL8 and gastric cancer: These analyses revealed that in comparison to healthy individuals patients with early gastric cancer have significantly higher mean values of IL-6 levels, IL-6/IL-8 and IL-6/IL-10 ratios, as well as, lower IL-8 concentrations; whereas IL-10 concentrations and values of IL-8/IL-10 ratio were almost reaching statistical significance (p = 0.09 and p = 0.07, respectively; depicted on Fig. 3).