Multivariate analysis (Table 2) showed that AFP, diameter of largest lesion, tumor number and vascular invasion were independent prognostic factors for OS, along with NLR (HR 1.32, 95% CI 1.07–1.62, P = 0.009), or dNLR (HR 1.26 95% CI 1.03–1.52, P = 0.022), or M/GLR (HR 1.40 95%CI 1.14–1.71, P = 0.001). The gene discussed is AFP; the disease is neoplasm.