Using 8 freshly collected clinical pancreatic cancer samples, we found that miR-744 expression was inversely correlated with expression of β-catenin (r = 0.62, P < 0.05), SFRP1 (r = −0.89, P < 0.05), GSK3β (r = −0.61, P < 0.05), TLE3 (r = −0.82, P < 0.05) (Fig. 6A–6C). Here, SFRP1 is linked to familial pancreatic carcinoma.