MIF is also expressed in human and murine platelets and is secreted from platelets upon activation.[16] MIF was shown to be involved in inflammatory atherosclerosis pathogenesis and is implicated in modulation of disease progression.[15, 17] Plaque regression and a more stable plaque phenotype have been shown through MIF blockade in a pre-clinical setting.[12] Whilst MIF is in spotlight of experimental atherosclerosis research, clinical studies investigating MIFs impact are rare to date. Here, MIF is linked to atherosclerosis.