MTOR and Crohn disease: We tested this by performing ‘Gene-set Enrichment Analysis'15 with molecules implicated in translational control (corresponding to the eIF2, eIF44 and mTOR proteins and mRNA transcripts in Table 1) in genome-wide association data,14 and the effect was significantly associated with schizophrenia following Bonferroni correction (P=0.019; Supplementary Data set 5), and showed a trend association with bipolar disorder (P=0.084), but not Crohn's disease or type 2 diabetes (Supplementary Data set 5).