When the SOCS3/A20 expression level was classified as high or low, no significant correlation was found between SOCS3/A20 expression and certain clinicopathological parameters, including gender, age, tumor site, histological patterns, vascular invasion, serum CEA and CA19-9 levels and HBV infection status (Table 1, all P values > 0.05). This evidence concerns the gene TNFAIP3 and neoplasm.