WNT2 and colorectal carcinoma: However, chromatin immunoprecipitation assay (ChIP) assays of WNT2 promoter showed that EZH2 did not occupy to WNT2 promoter in CRC cells (HCT116, KM12, and HT15), while it occupies WNT2 promoter in 293T and IECs (CCD841CoN) (Figure 4C).