Five of the genes displayed either modestly decreased (MIEN1, PGAP3, GRB7, and ERBB2; 1.24–2.01-fold) or increased expression (IKZF3; 2.41-fold) in biopsies from inflamed, compared with noninflamed, colonic IBD mucosa (Table 3). The gene discussed is GRB7; the disease is inflammatory bowel disease.