MIEN1 and inflammatory bowel disease: Similar effects were seen separately for CD and UC, although only nominal significance (P < 0.05) was reached for IKZF3 in CD and for MIEN1 in both UC and CD. CSF3 expression was increased at least 116-fold in inflamed, compared with noninflamed, biopsies from the overall IBD group and from the separate disease subentities (Table 3).