The granulocyte colony-stimulating factor (encoded by CSF3) stimulates the production, survival, and activity of neutrophils [28], and the granulocyte colony-stimulating factor produced by nonhematopoietic cells promotes neutrophil trafficking to the synovial tissue during collagen-induced arthritis in a murine model of rheumatoid arthritis [29]. The gene discussed is CSF3; the disease is rheumatoid arthritis.