PLAU and urinary bladder carcinoma: Analysis of the ratios of ETS2 (v-ets erythroblastosis virus E26 oncogenehomolog 2) mRNA and uPA (urokinase plasminogen activator) mRNA in cell-free RNAin total urine (without centrifugation/precipitation of the cells) make itpossible to diagnose bladder cancer with 100% specificity and 75.4% sensitivity[61].