GPC1 and neoplasm: Immunohistochemical analysis of glypican-1 protein showed a very weak staining in most of the cells, although certain specific ones displaying neuroendocrine features showed intense immunostaining, On the other hand, it must be taken into account that the values of transcription quantified by PCR are not probably revealing these differences, since it must be considered that the data are affected by the decrease or absence of neuroendocrine cells with high expression levels in the tumor stroma.